GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THCA | cis | rs1030420 | 1 | rs7014273 | chr8:67358694 | ADHFE1 | chr8:67344718-67381042:+ | 0.26 | 5.46 | 7.52E-8 | Blood metabolite levels |
| THCA | cis | rs1030420 | 1 | rs7014273 | chr8:67358694 | C8orf46 | chr8:67405491-67430757:+ | -0.3 | -5.02 | 7.27E-7 | Blood metabolite levels |
| THCA | cis | rs4493873 | 1 | rs7014578 | chr8:92077568 | LRRC69 | chr8:92114847-92231464:+ | -0.22 | -3.62 | 0.000323 | Migraine - clinic-based |
| THCA | cis | rs7017914 | 1 | rs7017914 | chr8:71591203 | XKR9 | chr8:71581600-71648176:+ | 1.06 | 27.98 | 1.01E-102 | Bone mineral density |
| THCA | cis | rs7267979 | 1 | rs7018 | chr20:25278261 | ENTPD6 | chr20:25176339-25207360:+ | -0.31 | -6.94 | 1.26E-11 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs7018 | chr20:25278261 | FAM182A | chr20:26035250-26067552:+ | -0.18 | -3.41 | 0.000699 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs7018 | chr20:25278261 | FAM182B | chr20:25744102-25848786:- | 0.26 | 5.52 | 5.64E-8 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs7018 | chr20:25278261 | NINL | chr20:25433338-25566153:- | -0.35 | -7.26 | 1.6E-12 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs7018 | chr20:25278261 | PYGB | chr20:25228706-25278647:+ | -0.15 | -3.73 | 0.000212 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs2129782 | 1 | rs7018226 | chr8:89446335 | MMP16 | chr8:89049462-89339717:- | 0.33 | 5.32 | 1.58E-7 | Electrodermal activity |
| THCA | cis | rs7267979 | 1 | rs7019 | chr20:25278278 | ENTPD6 | chr20:25176339-25207360:+ | -0.31 | -7.15 | 3.21E-12 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs7019 | chr20:25278278 | FAM182A | chr20:26035250-26067552:+ | -0.18 | -3.41 | 0.000708 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs7019 | chr20:25278278 | FAM182B | chr20:25744102-25848786:- | 0.26 | 5.44 | 8.73E-8 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs7019 | chr20:25278278 | NINL | chr20:25433338-25566153:- | -0.36 | -7.5 | 3.18E-13 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs7019 | chr20:25278278 | PYGB | chr20:25228706-25278647:+ | -0.14 | -3.55 | 0.00042 | Liver enzyme levels (alkaline phosphatase) |